Bioreactor
Level and pressure measurement in the production of enzymes, proteins and antibodies
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Process data
Measuring task:
Level and pressure measurement
Measuring point:
Reactor
Measuring range up to:
5 m
Medium:
Microorganisms
Process temperature:
+20 … +80 °C
Process pressure:
-1 … +5 bar
Special challenges:
Frequent cleaning cycles
Application
Some pharmaceutical companies use bioreactor vessels to cultivate particular cells or microorganisms required for certain treatments. The very high level of hygiene required means the vessels and all associated parts must be easy to thoroughly clean, because even the slightest contamination with other organisms can lead to an aborted production run. These reactors are mainly "batch-fed", where they are completely filled at the start and not emptied again until the process is completed. The pressure and level in the reactor have to be monitored continuously during process in order to obtain a high-quality yield.
Your benefit
Reliable
Unaffected by extreme process conditions
Cost effective
Reliable, continuous operation with absolute hygiene
User friendly
Easy adjustment and setup, as internals do not interfere
Recommended products
VEGAPULS 6X
Radar sensor for continuous level measurement in the bioreactor
- The front-flush, encapsulated antenna is easy to clean and resistant to the extreme conditions of the SIP and CIP processes
- Maximum utilization of the reactor, measurement is unaffected by changing products and process conditions
- The small beam angle and good focusing of the sensor allows easy alignment
Measuring range - Distance
120 m
Process temperature
-196 ... 450 °C
Process pressure
-1 ... 160 bar
VEGABAR 83
Pressure transmitter for continuous pressure monitoring in the bioreactor and in the pipeline
- The welded, 50 μm-thick Alloy diaphragm with aseptic process fitting is a hygienically optimal and reliable solution
- Neither the chemical cleaning cycles nor the thermal shocks after sterilization can affect the diaphragm
- Pressure measurement in the pipeline for monitoring CIP cleaning processes
Measuring range - Distance
-
Measuring range - Pressure
-1 ... 1000 bar
Process temperature
-40 ... 200 °C
VEGABAR 38
Pressure monitoring with IO-Link connection in the supply line of the heating medium
- Reliable measurement thanks to fast response time
- Robust ceramic CERTEC® measuring cell guarantees a long service life
- Simple operation thanks to VDMA menu structure and integrated display
Measuring range - Pressure
-1 ... 60 bar
Process temperature
-40 ... 130 °C
Accuracy
0.3 %
